Publications

Newcastle University

Comming soon

Yale University

11. Exploiting evolutionary trade-offs for post-treatment management of drug-resistant populations.

Melnikov SV, Stevens DL, Fu X, Kwok HS, Zhang J-T, Shen Y, Sabina J, Lee K, Lee H, Söll D (2020)
Proceedings of the National Academy of Sciences  PDF | SI

10. Archaeal ribosomal proteins possess NLS-type motifs: implications for the origin of the cell nucleus.

Melnikov SV, HS Kwok, K Manakongtreecheep, A van den Elzen, CC Thoreen, D Söll (2020)
Molecular Biology and Evolution, 37(1), 124-133 PDF | SI

9. Engineered tRNA synthetases with improved selectivity toward noncanonical amino acids

Kwok HS , Vargas-Rodriguez O, Melnikov SV, Söll D (2019)
ACS Chemical Biology 14 (4), 603-612 PDF | SI

8. tRNA synthetases and tRNAs for an expanded genetic code: what makes them orthogonal?

Melnikov SV, Söll D (2019)
International Journal of Molecular Sciences 20 (8), 1929-1930 PDF | SI

7. Mechanistic insights into the slow peptide bond formation with D-amino acids

Melnikov SV, Khabibullina NF, Mairhofer E, Vargas-Rodriguez O, Reynolds NM, Micura R, Söll D, Polikanov YS (2018)
Nucleic Acids Research 47 (4), 2089-2100 PDF | SI

6. Loss of protein synthesis quality control in host-restricted organisms

Melnikov SV, van den Elzen A, Stevens DL, Thoreen CC, Söll D (2018)
Proceedings of the National Academy of Sciences 115 (49), E11505-E11512 PDF | SI

5. Muller’s ratchet and ribosome degeneration in the obligate intracellular parasites Microsporidia

Melnikov SV, Manakongtreecheep K, Rivera K, Makarenko A, Pappin D, Söll D (2018)
International Journal of Molecular Sciences 19 (12), 4125 PDF | SI

4. Error-prone protein synthesis in parasites with the smallest eukaryotic genome

Melnikov SV, Rivera K, Ostapenko D, Makarenko A, Sanscrainte N, Becnel J, Solomon M, Texier C, Pappin D, Söll D (2018)
Proceedings of the National Academy of Sciences 115 (27), E6245-E6253 PDF | SI

3. Revising the structural diversity of ribosomal proteins across the three domains of life

Melnikov SV, Manakongtreecheep K, Söll D (2018)
Molecular Biology and Evolution 35 (7), 1588-1598 PDF | SI

2. RNA binding by the anticancer drug cisplatin

Melnikov SV, Söll D, Steitz TA, Polikanov YS (2016)
Nucleic Acids Research 44 (10), 4978-4987 PDF | SI

1. Insights into the role of rRNA modifications in protein synthesis and ribosome assembly

Polikanov YS#, Melnikov SV#, Söll D, Steitz TA (2015)
Nature Structural & Molecular Biology 22 (4), 342 PDF | SI

Strasbourg University

7. Insights into the role of diphthamide on longation factor 2 in mRNA reading-frame maintenance

Pellegrino S, Demeshkina N, Mancera-Martinez E, Melnikov SV, Simonetti A,  Myasnikov A, Yusupov M, Yusupova G, Hashem Y (2018)
Journal of Molecular Biology 430 (17), 2677-2687 PDF | SI

6. Molecular insights into protein synthesis with proline residues

Melnikov SV, Mailliot J, Rigger L, Neuner S, Shin BS, Yusupova G, Yusupov M (2016)
EMBO Reports 17 (12), 1776-1784 PDF | SI

5. Structure of hypusine-containing translation factor eIF5A bound to a rotated eukaryotic ribosome

Melnikov SV, Mailliot J, Shin BS, Rigger L, Yusupova G, Micura R, Dever TE, Yusupov M (2015)
Journal of Molecular Biology 428 (18), 3570-3576 PDF | SI

4. Insights into the origin of the nuclear localization signals in conserved ribosomal proteins

Melnikov SV, Ben-Shem A, Yusupova G, Yusupov M (2015)
Nature Communications 6, 7382 PDF | SI

3. Crystal structure of the 80S yeast ribosome

Jenner L, Melnikov SV, de Loubresse NG, Ben-Shem A, Iskakova M, Urzhumtsev A, Meskauskas A, Dinman J, Yusupova G, Yusupov M (2012)
Current Opinion in Structural Biology 22 (6), 759-767 PDF | SI

2. One core, two shells: bacterial and eukaryotic ribosomes

Melnikov SV, Ben-Shem A, de Loubresse NG, Jenner L, Yusupova G, Yusupov M (2012)
Nature Structural and Molecular Biology 19 (6), 560 PDF | SI

1. The structure of the eukaryotic ribosome at 3.0 Å resolution

Ben-Shem A#, de Loubresse NG#, Melnikov SV#, Jenner L, Yusupova G, Yusupov M (2011)
Science 334 (6062), 1524-1529 PDF | SI

Moscow State University

4. Effect of prothymosin α and its mutants on the activity of the p53 tumor suppressor

Zakharova NI, Sokolov VV, Roudko VV, Melnikov SV, Vartapetian AB, Evstafieva AG (2008)
Molecular Biology 42 (4), 598-608 PDF | SI

3. Interaction with Keap1 does not lead to ubiquitination and degradation of prothymosin α

Melnikov SV, Evstafieva AG, Vartapetian AB (2007)
Molecular Biology 41 (5), 790-796 PDF | SI

2. New functions of a well-known protein: prothymosin α in defence from apoptosis and oxidative stress

Evstafieva AG, Karapetian RN, Rubtsov YP, Filonov GS, Abaeva IS, Fateeva TV, Melnikov SV, Chichkova NV, Vartapetian AB (2005)
Molecular Biology 39 (5), 631-645 PDF | SI

1. Nuclear oncoprotein prothymosin α binds Keap1 to regulate expression of oxidative stress-protecting genes

Karapetian RN, Evstafieva AG, Abaeva IS, Chichkova NV, Filonov GS, Rubtsov YP, Sukhacheva EA, Melnikov SV, Schneider U, Wanker EE, Vartapetian AB (2005)
Molecular and Cellular Biology 25 (3), 1089-1099 PDF | SI