Publications

Newcastle University

9. Evolution of drug-binding residues in eukaryotic ribosomes

Chan LI , Ekemezie CL, Brown CR , Helena-Bueno K, Williams T, Melnikov SV (2024)
bioRxiv PDF

8. Evolution of drug-binding residues in bacterial ribosomes

Ekemezie CL, Chan LI , Brown CR , Helena-Bueno K, Williams T, Melnikov SV (2024)
bioRxiv PDF

7. Hibernating ribosomes as drug targets?

Ekemezie CL, Melnikov SV (2024)
Frontiers in Microbiology (Review) PDF

6. Rippling life on a dormant planet: hibernation of ribosomes, RNA polymerases and other essential enzymes

Helena-Bueno K, Chan LI, Melnikov SV (2024)
Frontiers in Microbiology, 15:1386179 (Review) PDF

5. Gosha: a database of organisms with defined optimal growth temperatures

Helena-Bueno K, Brown CR, Konyk E, Melnikov SV (2024)
bioRxiv (Public Resource) PDF

4. The structure of dormant bacterial ribosomes reveals an elusive hibernation factor of protein synthesis

Helena-Bueno K, Rybak MYu, Ekemezie CL, Sullivan R, Brown CR, Dingwall C, Basle A, Schneider C, Connolly JPR, Blaza JN, Csörgő B, Moynihan PJ, Gagnon MG, Hill CH, Melnikov SV (2024)
Nature, 626:1125–1132 PDF

3. A conserved ribosomal protein has entirely different structures in different organisms

Schierholz L, Brown CR, Helena-Bueno K, Uversky VN, Barandun J, Melnikov SV (2023)
Molecular Biology and Evolution,41:msad254 PDF

2. Ribosomal proteins hold a more accurate record of thermal adaptation compared to rRNA

van den Elzen A, Helena-Bueno KBrown CR, Chan LIMelnikov SV (2023)
Nucleic Acids Research, 51:8048–8059, PDF

1. “Lose-to-gain” adaptation to genome decay in the structure of the smallest eukaryotic ribosomes

Nicholson D, Salamina M, Panek J, Helena-Bueno K, Brown CR, Hirt RP, Ranson NA, Melnikov SV (2022)
Nature Communications,13:591  PDF | SI