In late 1970s, agriculture encountered a major crisis in pesticide resistance leading to the near-collapse of the cotton industry in several countries. This crisis forced the industry to devise the Integrated Pest Management (IPM), an approach that aims to minimize the risk of pesticide resistance by limiting pesticide use and by trying to manage pests rather than trying to eradicate them. Our recent paper provides a small “stone” for the emerging “building” of a similar approach – adaptive therapy – that aims to improve the way use antimicrobial and anticancer drugs: https://www.pnas.org/content/early/2020/07/10/2003132117
Please check out this wonderful blog post by Maria O’Hanlon discussing our work and this emerging new trend in more sustainable drug application: https://bit.ly/3fs45sr