GSHT: a database of organisms with defined optimal growth temperatures

This database was created for scientists exploring how organisms adapt to certain temperatures, at the scale from individual molecules to entire genomes. This database was also created for engineers striving to find the simplest and the most economical ways to endow biological molecules and organisms with the desired tolerance to heat and cold. We hope you like it here, and you are very welcome!

Download data
These datasets describe bacteria, archaea, and eukaryotes with experimentally defined optimal growth temperature and genomic sequences deposited in the NCBI genome database:

Check the growth temperature
Enter your organisms name and check its optimal growth temperature:

Enter Organism name above & Submit to check Optimal Growth Temperature.

Retrieve sequences of your protein of interest :
Enter your protein name (as listed at Uniprot) and retrieve its sequences arranged by the optimal growth temperature of corresponding organisms

Enter Protien name above & Submit to get downloadable csv files.

Studying protein adaptation to heat and cold through comparative analysis of thousands of genomes.